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. 2024 Jun 14;29(12):2833. doi: 10.3390/molecules29122833

Scheme 16.

Scheme 16

Synthesis of vinyl iodide 110. (i) D-proline, PhNO, CHCl3, 0 °C to rt; (ii) NaBH4, EtOH, then Zn, AcOH, 82%, 98% ee. Details for the preparation of 110 is given in reference [68].