Table 5.

Effect of CE treatment of male rates on embryonic pre- and post-implantation death of day 20 of pregnancy.

Parameters		Experimental Groups a
		♂  ×  ♀	♂  ×  ♀	♂  ×  ♀	♂  ×  ♀
		H2O × Intact	CE, 100 mg/kg × Intact	CE, 500 mg/kg × Intact	CE, 1000 mg/kg × Intact
Number of pregnant female rats investigated		7	7	7	7
Embryonic Death (%) b	Pre-implantation	7.7 ± 0.8	7.6 ± 0.7 ns	7.2 ± 0.3 ns	6.4 ± 0.6 ns
	Post-implantation	4.7 ± 0.5	4.5 ± 0.3 ns	4.2 ± 0.3 ns	3.8 ± 0.4 ns
Embryonic weight on day 20 (g) b		2.4 ± 0.1	2.3 ± 0.1 ns	2.4 ± 0.03 ns	2.3 ± 0.1 ns

^a—male rats were orally treated with either H₂O (control) or CE (100, 500, or 1000 mg/kg bw/day) for 60 days before mating; ^b—mean ± SE. ^ns—the differences between the CE-treated and control groups were not statistically significant.