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Regulatory lymphocytes prior to and following 1st dose and 2nd dose of SARS-CoV-2 vaccine. CD4Treg increased after 2nd dose in HC; however, no such increase was observed in CVID. TFR cells increased after 1st and 2nd doses in both HC and CVID. A reverse effect was observed for CD8Treg. In HC, CD8Treg markedly increased whereas in CVID CD8Treg markedly decreased after 1st dose of vaccine.
