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. 2024 May 25;16(2):420–431. doi: 10.3390/pediatric16020036

Table 1.

A summary of symptoms of KS.

Physical, Reproductive, and Endocrine Symptoms Lannguage Deficits Executive Dysfunction Social Impairments
  • Gynecomastia

  • Small testes

  • Impaired spermatogenesis

  • Azoospermia

  • Testicular failure

  • Androgen deficiency

  • Elevated gonadotropin levels

  • Delayed babbling, lexical, and syntactic abilities

  • Decreased vocabulary and comprehension

  • Impairments in complex language processing, expressive vocabulary, verbal memory, and expressive grammar

  • Challenges in understanding metaphors and implied meanings

  • Reading/writing difficulties

  • Persistent phonological errors in speech production

  • Deficits in information processing speed

  • Selective and sustained attention difficulties

  • Response inhibition challenges

  • Cognitive flexibility issues

  • Conceptualization difficulties

  • Problems with initiating, planning, and goal setting

  • Lower working memory capabilities

  • Shy and withdrawn behavior

  • Challenges in perceiving, comprehending, and conveying social signals

  • Deficits in interpreting facial expressions and affective nuances in tone of voice

  • Difficulties in academic settings and employment acquisition/retention

  • Obstacles in forming intimate relationships