. 2024 May 23;16(6):700. doi: 10.3390/pharmaceutics16060700

Table 1.

Synergistic effect of Protium spruceanum extract and mupirocin antibiotic.

Bacteria	Extract	Antibiotic	Combination	ICIF
Bacteria	MIC (μg/mL)	MIC (μg/mL)	MIC (μg/mL)	ICIF
S. aureus	2000 ± 577 ^a	0.13 ± 0.07 ^a	250 ± 72 *^a/0.06 ± 0 ^#a	0.62 ± 0.25 ^a
MRSA	2000 ± 0 ^a	0.06 ± 0.02 ^a	125 ± 36 *^a/0.03 ± 0.01 ^#a	0.56 ± 0.17 ^a

MIC: Minimum inhibitory concentration; ICIF: inhibitory concentration index fractionation; * = extract concentration; ^# = mupirocin concentration. Same lowercase letter indicate no significant statistical difference in the same column (p < 0.05).