Table 4.

IC₅₀ values on the trypomastigote form of T. cruzi Dm28 and Vero mammalian cells.

Compound	T. cruzi (µM)		Vero Cells (µM)	SI [b]
	T [c]	E [d]		T [c]	E [d]
3	>400	>400	>400	nd [a]	nd
5	>400	400 ± 3	>400	nd	nd
8	>400	> 400	398.1 ± 0.3	nd	nd
9	400 ± 2	166 ± 4	244.5 ± 0.5	0.6	1.5
11	400 ± 5	>400	125.9 ± 0.1	0.3	nd
12	>400	>400	141 ± 6	nd	nd
13	>400	>400	102 ± 6	nd	nd
16	>400	>400	141 ± 4	nd	nd
17	>400	>400	>400	nd	nd
Nfx	10.04 ± 0.1	-	172.9 ± 0.1	17.9	-

^[a] not define, ^[b] Selectivity index $SI=\frac{{IC}_{50}Vero cells}{{IC}_{50}\mathit{T.\; cruzi}}$ , ^[c] trypomastigote, ^[d] epimastigote.