Conventional Chemotherapy |
Intravenous |
High systemic toxicity, non-specific |
Established method, rapid distribution |
Severe side effects, non-targeted |
Nanoparticle-Based Delivery |
Nanoparticles |
Improved targeting, reduced toxicity |
Enhanced EPR effect, customizable |
Complex fabrication, potential toxicity |
Scaffold-Based Delivery |
3D Scaffolds |
Sustained release, targeted delivery |
Reduced side effects, multifunctional |
Manufacturing complexity, potential immune response |
Injectable Hydrogels |
Self-assembling peptides |
Prolonged drug release, localized delivery |
Minimally invasive, biocompatible |
Stability issues, potential for uneven drug distribution |
Drug-Coated Scaffolds |
Coated with anti-cancer drugs |
Inhibition of cancer cell proliferation |
Localized delivery, reduced systemic exposure |
Risk of scaffold degradation, need for precise engineering |