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. 2024 Jun 14;16(6):802. doi: 10.3390/pharmaceutics16060802

Table 1.

Comparative Data on Treatment Outcomes: Scaffold-Based Systems vs. Conventional Therapies.

Treatment Method Drug Delivery System Key Outcomes Advantages Limitations
Conventional Chemotherapy Intravenous High systemic toxicity, non-specific Established method, rapid distribution Severe side effects, non-targeted
Nanoparticle-Based Delivery Nanoparticles Improved targeting, reduced toxicity Enhanced EPR effect, customizable Complex fabrication, potential toxicity
Scaffold-Based Delivery 3D Scaffolds Sustained release, targeted delivery Reduced side effects, multifunctional Manufacturing complexity, potential immune response
Injectable Hydrogels Self-assembling peptides Prolonged drug release, localized delivery Minimally invasive, biocompatible Stability issues, potential for uneven drug distribution
Drug-Coated Scaffolds Coated with anti-cancer drugs Inhibition of cancer cell proliferation Localized delivery, reduced systemic exposure Risk of scaffold degradation, need for precise engineering