Table 2.

Types of Scaffold Materials Used in Oral Cancer Treatment.

Scaffold Material	Type (Natural/ Synthetic)	Key Properties	Applications in Oral Cancer Treatment
Collagen	Natural	Biocompatible, promotes cell adhesion	Used for creating 3D scaffolds to support tissue regeneration and drug delivery
Matrigel	Natural	Rich in ECM proteins, supports cell growth	Applied in tumor models for drug testing and delivery
Silk	Natural	High tensile strength, biocompatible	Used in scaffolds for controlled drug release and tissue engineering
Polyethylene Glycol (PEG)	Synthetic	Hydrophilic, biocompatible, tunable degradation rate	Used in hydrogels for sustained drug release and provides robust support for cell growth
Poly(lactic-co-glycolic acid) (PLGA)	Synthetic	Biodegradable, controllable degradation rate	Utilized in nanoparticles for targeted drug delivery, mimics physiological environment
Chitosan	Natural	Biodegradable, antimicrobial properties	Used for creating injectable hydrogels for local drug delivery