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. 2024 Jun 4;16(6):765. doi: 10.3390/pharmaceutics16060765

Table 3.

Papp measured at different flow rate ratios (1, 1.25, 2) after 1, 2, 3, and 4 h on the microfluidic setup with or without a membrane on the chip. Lines with the letter a showed a significant difference at the 0.05 level.

Papp (10−6 cm/s)
Ratio 1 (25/25) a 1.25 (25/20) a 2 (30/15) a
Time w/Membrane w/o Membrane w/Membrane w/o Membrane w/Membrane w/o Membrane
1 h 8.37 ± 5.58 8.43 ± 5.59 11.34 ± 4.14 22.02 ± 7.81 30.78 ± 5.47 38.20 ± 6.64
2 h 4.50 ± 0.97 5.14 ± 2.10 13.59 ± 4.17 15.55 ± 1.22 34.15 ± 2.74 38.10 ± 3.21
3 h 4.53 ± 1.31 5.61 ± 0.61 14.70 ± 3.63 15.93 ± 1.80 35.54 ± 2.25 38.46 ± 8.36
4 h 4.38 ± 1.48 6.54 ± 2.75 12.09 ± 3.62 15.74 ± 1.81 31.13 ± 2.97 38.72 ± 10.20