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Schematic representation of each approach described to obtain Stratum Corneum lipid mixture-based surrogates for in vitro permeation evaluation. (A) Spraying by airbrush. Adapted with permission from [58]. Copyright 2006, Elsevier. (B) Skin-Parallel Artificial Membrane Permeability Assay (Skin-PAMPATM). Adapted with permission from [197]. Copyright 2013, Elsevier. (C) Phospholipid Vesicle-based Permeation Assay (PVPA). Adapted with permission from [189]. Copyright 2013, Wiley.
