Table 3.
Internally–Externally Validated the Model’s Performance
| Internally-externally validated performance | Prediction model of FEP | |||||
|---|---|---|---|---|---|---|
| The UK | The Netherlands | Spain | France | Italy | Brazil | |
| Sample size, n | 582 | 406 | 426 | 252 | 467 | 494 |
| Number of outcome events, n | 246 | 196 | 204 | 105 | 187 | 192 |
| Proportion of outcome events | 0.42 | 0.48 | 0.48 | 0.42 | 0.40 | 0.39 |
| AUROC | 0.84 (95% CI = 0.82–0.85) | 0.84 (95% CI = 0.82–0.85) | 0.84 (95% CI = 0.83–0.86) | 0.84 (95% CI = 0.82–0.85) | 0.86 (95% CI = 0.84–0.87) | 0.85 (95% CI = 0.83–0.87) |
| Calibration intercept (α) | 0.23 | 0.56 | 0.14 | 0.13 | −0.24 | −0.19 |
| Calibration slope (β) | 1.71 | 1.61 | 1.22 | 1.77 | 0.85 | 1.11 |
| Sensitivity | 75.0% | 73.9% | 74.0% | 74.8% | 77.6% | 78.0% |
| Specificity | 75.6% | 79.3% | 78.1% | 77.0% | 76.7% | 76.8% |
Note: AUROC, area under the receiver operating characteristic curve; CI, confidence intervals.