Table 3.

Factor loading of total symptom score in PD patients (N = 602).

Symptom	Body symptom cluster	Gastro-intestinal symptom cluster	Mood symptom cluster	Sexual disorder symptom cluster	Skin and sleep symptom cluster
Nausea		0.91
Vomiting		0.91
Decreased appetite		0.57
Muscle cramps	0.62
Restless legs	0.56
Numbness or tingling in feet	0.67
Feeling tired or lack of energy	0.64
Bone or joint pain	0.64
Headache
Muscle soreness	0.61
Difficulty concentrating	0.65
Dry skin					0.50
Itching					0.45
Worrying			0.83
Trouble falling asleep					0.88
Trouble staying asleep					0.82
Feeling irritable			0.80
Feeling sad			0.88
Feeling anxious			0.86
Depression			0.83
Decreased interest in sex				0.95
Difficulty become sexual aroused				0.95
Eigenvalue	2.42	1.76	6.98	1.25	1.63
Variance contribution rate (%)	11.00	8.00	31.71	5.68	7.43
Cumulative variance contribution rate (%)	42.71	50.71	31.71	63.82	58.14

This table displays the principal component analysis outcomes for 22 symptoms in PD patients, categorizing them into five clusters: body, gastro-intestinal, mood, sexual disorder, and skin and sleep symptom clusters. These clusters reflect the symptom patterns and their contribution to the overall symptom burden, with a total variance contribution rate of 63.82%. This indicates the extent to which these clusters capture the diverse symptomatology in PD patients, facilitating targeted therapeutic strategies.