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. 2024 Jun 26;17(6):e13858. doi: 10.1111/cts.13858

FIGURE 7.

FIGURE 7

Male NF1 +/ex42del miniswine with cNFs show a cautious walking strategy in a kinematic gait analysis. (a) Principal component score of most significant variables indicates that male NF1 +/ex42del miniswine with cNFs have significant gait abnormalities at 12 and 15 months of age. There is lost at 18 months of age, likely due to a lower n. Among these top variables, cNF‐burdened NF1 +/ex42del males had (b) increased stride time, (c) increased step time, (d) increased integrated pressure, (e) increased walk ratio, (f) decreased cadence, (g) decreased walk velocity, (h) increase in stance (time with feet on ground), and (i) decrease swing (d time spent with feet off the ground). PCA implemented in R utilizing the FactorMineR package. n = 3–4 NF1 +/ex42del  + cNFs; n = 6–22 NF1 +/ex42del ‐cNFs; n = 7–17 WT. One‐way ANOVA, Tukey post hoc. *p < 0.05, **p < 0.01. Mean ± SEM.