Fig. 1. Deconstructing synthetic biology technologies across scales.

A schematic representation of the deconstruction framework: biotechnologies can be deconstructed along scales to identify biological phenomena that are important to the technology at each scale, understand the principles by which these phenomena work at that scale, and identify the important interfaces between scales where engineering challenges often arise. Deconstructing technologies along scales allows multidisciplinary concepts to be mapped and applied at individual scales (annotated) and allows new technologies to be reconstructed by combining elements and applying concepts at each scale.