Table 1.
Demographic and clinical characteristics of 2451 patients diagnosed with second primary lung cancer.
| Characteristic | Results | |||
| Age (years), mean (SD) | 63.5 (9.2) | |||
| Race, n (%) | ||||
|
|
White | 2062 (84.1) | ||
|
|
Black | 240 (9.8) | ||
|
|
Other | 149 (6.1) | ||
| Sex, n (%) | ||||
|
|
Male | 1137 (46.4) | ||
|
|
Female | 1314 (53.6) | ||
| Relative location, n (%) | ||||
|
|
Ipsilateral | 815 (33.3) | ||
|
|
Contralateral | 1636 (66.7) | ||
| Diagnostic interval (months), mean (SD) | 101.0 (47.6) | |||
| Initial primary lung cancer | ||||
|
|
Year of diagnosis, n (%) | |||
|
|
|
1988-1995 | 763 (31.1) | |
|
|
|
1996-2003 | 919 (37.5) | |
|
|
|
2004-2012 | 769 (31.4) | |
|
|
SEERa stage, n (%) | |||
|
|
|
Localized | 1538 (62.7) | |
|
|
|
Regional | 913(37.3) | |
|
|
Histology, n (%) | |||
|
|
|
ADCb | 1399 (57.1) | |
|
|
|
SCCc | 690 (28.2) | |
|
|
|
Other NSCLCd | 362 (14.8) | |
|
|
Grade, n (%) | |||
|
|
|
Well differentiated | 277 (11.3) | |
|
|
|
Moderately differentiated | 844 (34.3) | |
|
|
|
Poorly differentiated | 792 (32.3) | |
|
|
|
Undifferentiated | 115 (4.7) | |
|
|
|
Unknown | 423 (17.3) | |
|
|
Surgery, n (%) | |||
|
|
|
No surgery | 264 (10.8) | |
|
|
|
Sublevel resection | 295 (12) | |
|
|
|
Lobectomy | 1786 (72.9) | |
|
|
|
Pneumonectomy | 106 (4.3) | |
|
|
Chemotherapy, n (%) | |||
|
|
|
Yes | 465 (19) | |
|
|
|
No/unknown | 1986 (81) | |
|
|
Radiotherapy, n (%) | |||
|
|
|
Yes | 489 (20) | |
|
|
|
No/unknown | 1962 (80) | |
| Second primary lung cancer | ||||
|
|
Surgery, n (%) | |||
|
|
|
No surgery | 1603 (65.4) | |
|
|
|
Wedge resection | 295 (12) | |
|
|
|
Segmentectomy | 61 (2.5) | |
|
|
|
Other/inseparable sublevel resection | 87 (3.5) | |
|
|
|
Lobectomy | 352 (14.4) | |
|
|
|
Pneumonectomy | 53 (2.2) | |
|
|
Chemotherapy, n (%) | |||
|
|
|
Yes | 694 (28.3) | |
|
|
|
No/Unknown | 1757 (71.7) | |
|
|
Radiotherapy, n (%) | |||
|
|
|
Yes | 953 (38.9) | |
|
|
|
No/Unknown | 1498 (61.1) | |
|
|
Treatment, n (%) | |||
|
|
|
Only radiotherapy | 964 (35.3) | |
|
|
|
Only surgery | 759 (31.0) | |
|
|
|
Surgery + radiotherapy | 89 (3.6) | |
|
|
|
None | 739 (30.2) | |
aSEER: Surveillance, Epidemiology, and End Results.
bADC: adenocarcinoma.
cSCC: squamous cell carcinoma.
dNSCLC: non-small cell lung cancer.