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. 2024 Jun 12;10:e53354. doi: 10.2196/53354

Table 3.

Demographic and clinical characteristics of 716 patients diagnosed with second primary lung cancer after 2004.

Characteristic Results
Age (years), mean (SD) 65.8 (9.0)
Race, n (%)

White 608 (84.9)

Black 65 (9.1)

Other 43 (6)
Sex, n (%)

Male 310 (43.3)

Female 406 (56.7)
Relative location, n (%)

Ipsilateral 279 (39)

Contralateral 437 (61)
Interval, mean (SD) 74.2 (21.4)
Initial primary lung cancer

T stage, n (%)


T1 315 (44)


T2 277 (38.7)


T3 35 (4.9)


T4 66 (9.2)


Unknown 23 (3.2)

N stage, n (%)


N0 528 (73.7)


N1 80 (11.2)


N2 97 (13.5)


Unknown 11 (1.5)

Histology, n (%)


ADCa 406 (56.7)


SCCb 206 (28.8)


Other NSCLCc 104 (14.5)

Grade, n (%)


Well differentiated 94 (13.1)


Moderately differentiated 275 (38.4)


Poorly differentiated 211 (29.5)


Undifferentiated 18 (2.5)


Unknown 118 (16.5)

Surgery, n (%)


No surgery 131 (18.3)


Sublevel resection 106 (14.8)


Lobectomy 455 (63.5)


Pneumonectomy 24 (3.4)

Chemotherapy, n (%)


Yes 237 (33.1)


No/unknown 479 (66.9)

Radiotherapy, n (%)


Yes 174 (24.3)


No/unknown 542 (75.7)
Second primary lung cancer

Size (cm), n (%)


0-3 385 (53.8)


3-5 71 (9.9)


>5 56 (7.8)


Unknown 204 (28.5)

Surgery, n (%)


No surgery 533 (74.4)


Wedge resection 102 (14.2)


Lobectomy 81 (11.3)

Chemotherapy, n (%)


Yes 201 (28.1)


No/unknown 515 (71.9)

Radiotherapy, n (%)


Yes 309 (43.2)


No/unknown 407 (56.8)

Treatment, n (%)


None 224 (31.3)


Only radiation 309 (43.2)


Only wedge 102 (14.2)


Only lobectomy 81(11.3)

aADC: adenocarcinoma.

bSCC: squamous cell carcinoma.

cNSCLC: non-small cell lung cancer.