Figure 2.

Identification of commonly upregulated genes in S63845 resistant TNBC cell lines.A, volcano plot analysis of genes differentially expressed in resistant vs. sensitive cell lines identified the top 100 commonly upregulated genes in resistant cell lines (gene list seen in Table S1). B, 4 genes of interest whose levels (RPKM) are commonly significantly (p < 0.05) upregulated in resistant cell lines. Note that MCL1 levels are not different. C, lysates of the indicated 8 cell lines were immunoblotted for the indicated proteins with relative signal indicated. Representative results of three independent experiments. Original images are presented in Fig. S2.