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. 2024 Jun 26;7(6):e2417862. doi: 10.1001/jamanetworkopen.2024.17862

Table 3. Treatment Effects of RA and SA at 4 Weeks Posttreatment and 8 Weeks of Follow-Up.

Variable RA group, mean (SD) (n = 40) SA group, mean (SD) (n = 38) Difference (95% CI) P value
Primary outcome
PDSS
Posttreatment 115.20 (16.99) 95.45 (20.26) 19.75 (11.02 to 28.49) <.001
Follow-up 110.90 (18.68) 90.66 (22.47) 20.24 (11.51 to 28.98) <.001
Secondary outcome
ESS
Posttreatment 5.05 (3.73) 6.53 (5.02) −1.48 (−3.73 to 0.77) .20
Follow-up 5.53 (4.04) 7.55 (5.41) −2.03 (−4.23 to 0.22) .08
UPDRS
Posttreatment 29.70 (12.07) 41.42 (22.95) −11.72 (−19.90 to −3.55) .005
Follow-up 29.95 (11.55) 43.79 (19.54) −13.84 (−22.01 to −5.67) .001
UPDRS-III
Posttreatment 17.85 (9.05) 21.47 (9.88) −3.62 (−8.10 to 0.84) .11
Follow-up 18.35 (8.72) 22.58 (7.94) −4.23 (−8.70 to 0.24) .06
NMSS
Posttreatment 27.20 (12.18) 34.95 (15.75) −7.75 (−14.69 to −0.80) .03
Follow-up 30.83 (10.02) 36.87 (15.75) −6.04 (−12.98 to 0.90) .09
HAM-A
Posttreatment 8.63 (4.16) 12.89 (4.91) −4.27 (−6.58 to −1.96) <.001
Follow-up 12.60 (4.79) 18.24 (4.22) −5.64 (−7.95 to −3.33) <.001
PDQ-39
Posttreatment 24.43 (13.01) 33.26 (10.06) −8.84 (−15.08 to −2.60) .005
Follow-up 31.63 (13.12) 40.42 (11.36) −8.80 (−15.04 to −2.56) .006

Abbreviations: ESS, Epworth Sleepiness Scale; HAM-A, Hamilton Anxiety Rating Scale; NMSS, Non-Motor Symptoms Scale; PDQ-39, 39-item Parkinson Disease Questionnaire; PDSS, Parkinson Disease Sleep Scale; RA, real acupuncture; SA, sham acupuncture; UPDRS, Unified Parkinson Disease Rating Scale; UPDRS-III, section 3 of the Unified Parkinson Disease Rating Scale.