Table 3. Treatment Effects of RA and SA at 4 Weeks Posttreatment and 8 Weeks of Follow-Up.
Variable | RA group, mean (SD) (n = 40) | SA group, mean (SD) (n = 38) | Difference (95% CI) | P value |
---|---|---|---|---|
Primary outcome | ||||
PDSS | ||||
Posttreatment | 115.20 (16.99) | 95.45 (20.26) | 19.75 (11.02 to 28.49) | <.001 |
Follow-up | 110.90 (18.68) | 90.66 (22.47) | 20.24 (11.51 to 28.98) | <.001 |
Secondary outcome | ||||
ESS | ||||
Posttreatment | 5.05 (3.73) | 6.53 (5.02) | −1.48 (−3.73 to 0.77) | .20 |
Follow-up | 5.53 (4.04) | 7.55 (5.41) | −2.03 (−4.23 to 0.22) | .08 |
UPDRS | ||||
Posttreatment | 29.70 (12.07) | 41.42 (22.95) | −11.72 (−19.90 to −3.55) | .005 |
Follow-up | 29.95 (11.55) | 43.79 (19.54) | −13.84 (−22.01 to −5.67) | .001 |
UPDRS-III | ||||
Posttreatment | 17.85 (9.05) | 21.47 (9.88) | −3.62 (−8.10 to 0.84) | .11 |
Follow-up | 18.35 (8.72) | 22.58 (7.94) | −4.23 (−8.70 to 0.24) | .06 |
NMSS | ||||
Posttreatment | 27.20 (12.18) | 34.95 (15.75) | −7.75 (−14.69 to −0.80) | .03 |
Follow-up | 30.83 (10.02) | 36.87 (15.75) | −6.04 (−12.98 to 0.90) | .09 |
HAM-A | ||||
Posttreatment | 8.63 (4.16) | 12.89 (4.91) | −4.27 (−6.58 to −1.96) | <.001 |
Follow-up | 12.60 (4.79) | 18.24 (4.22) | −5.64 (−7.95 to −3.33) | <.001 |
PDQ-39 | ||||
Posttreatment | 24.43 (13.01) | 33.26 (10.06) | −8.84 (−15.08 to −2.60) | .005 |
Follow-up | 31.63 (13.12) | 40.42 (11.36) | −8.80 (−15.04 to −2.56) | .006 |
Abbreviations: ESS, Epworth Sleepiness Scale; HAM-A, Hamilton Anxiety Rating Scale; NMSS, Non-Motor Symptoms Scale; PDQ-39, 39-item Parkinson Disease Questionnaire; PDSS, Parkinson Disease Sleep Scale; RA, real acupuncture; SA, sham acupuncture; UPDRS, Unified Parkinson Disease Rating Scale; UPDRS-III, section 3 of the Unified Parkinson Disease Rating Scale.