Figure 4.
Neuropathological examination of DTV- and POWV-infected mouse spinal cords. Spinal cords were harvested at the time of euthanasia. Uninfected mouse with normal structures shown in (A,D) the cervical region (black arrow shows motor neuron in ventral horn), (G) thoracic region, and (J) lumbar region. DTV-infected mouse (B) cervical region, (E) motor neuron (black arrow) in dorsal horn, (H) thoracic region, and (K) lumbar region. POWV-infected mouse with (C) meningoencephalitis (red arrow) in cervical region, (F) absent and degenerating motor neuron (black arrow) in dorsal horn, and infiltrations in (I) thoracic and (L) lumbar regions.