Table 1.

Effectiveness of different bovine alphaherpesvirus vaccine formulations in neutralizing the antibodies produced in guinea pig and bovine experiments.

Vaccine Formulations	Guinea Pig Experiment	Bovine Experiment
Effect of vaccines formulation	<0.0001	<0.0001
Effect of time	0.0017	<0.0001
Interaction vaccine × time	<0.0001	<0.0001
Vaccine A	4.00 ± 0.00	Reproved
Vaccine B	20.00 ± 6.66	20.00 ± 4.51
Vaccine C	5.42 ± 0.90	Reproved
Vaccine D	28.66 ± 8.10	84.76 ± 27.53
Vaccine E	4.00 ± 0.00	Reproved
Vaccine F	6.33 ± 1.34	Reproved
Vaccine G	4.00 ± 0.00	Reproved
Vaccine H	No-tested	48.74 ± 9.27
Non-vaccinated Guinea pig and bovine model	4.00 ± 0.00

Guinea pig experiment was conducted to screen vaccines for the second experiment. Reproved—vaccines not selected for the second bovine experiment because of the low antibody titers developed after vaccination protocols; virus neutralization antibodies expressed as the mean and standard error. The effects of the vaccine group, time, and interaction between the group and time were determined using a MIXED models procedure.