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. 2024 Jun 4;16(6):908. doi: 10.3390/v16060908

Table 3.

Compounds disturbing cellular lipidome homeostasis as potential candidate antivirals.

Virus Compounds References
Rotavirus TOFA; [isoproterenol + IBMX] [2,17]
Hepatitis C virus Cyclophilin inhibitors blocking viral RNA replication [42]
Enterovirus CAY10499 (hormone-dependent lipase inhibitor) and atglistatin (adipose triglyceride lipase inhibitor), both reducing viral replication [36]
SARS-CoV-2 drugs reducing cholesterol synthesis and esterification, LD formation, and ceramide biosynthesis [7,9,43]
HIV-1 neutral sphingomyelinase 2 inhibitor (PDDC) blocking maturation and full infectivity of HIV-1 particles [38,39]