Figure 3.

M12 anti-S1 and anti-N log10 concentrations for BCG vs. placebo stratified by number of immune events. Abbreviations: Inf = infection; Inf + Vac1 = infection and one dose of a COVID vaccine; Inf + Vac2 = infection and two doses of a COVID vaccine; Vac1 = one dose of a COVID vaccine; Vac2 = two doses of a COVID vaccine. Systemic antibody concentrations were log₁₀-transformed (after adding a pseudocount of 1). An immune event was defined as one SARS-CoV-2 infection or one dose of a COVID-19 vaccine. The blue point range indicates the mean and standard deviation of the log₁₀ concentrations. Statistical testing (****) shows the significance for within-group comparisons. All statistical testing between BCG and placebo groups were non-significant. ns: non-significant, *: p <= 0.05, **: p <= 0.01, ***: p <= 0.001, ****: p <= 0.0001.