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NSP2 CTR Conformations and Putative Inter-Octamer Chains. (A) SA11 NSP2 octamer (PDB no. 4G0A) from Hu et al. is shown in ribbon form (cyan), with the flexible CTRs highlighted in orange. Representative open and closed CTRs are labeled. (B) Cartoon image of putative NSP2 inter-octamer chains. Under some crystallography conditions, the open CTR of one octamer can interact with the body of a neighboring octamer (and vice-versa) via a domain-swapping interaction.
