Structure of the BoNT/A LL-progenitor toxin complex (PTC; (left)) and the BoNT/A neurotoxin protein component (right). The complex shown here comprises the neurotoxin protein component (red/blue/yellow/gold), the non-toxin non-hemagglutinin protein (NTNH; purple), and several hemagglutinin (HA) proteins (shades of green). Images created by Lance Steward (AbbVie/Allergan Aesthetics) with Discovery Studio 2017 R2 (BIOVIA, Dassault Systèmes). Neurotoxin component image based on PDB ID 3BTA; Lacy et al. [44]. LL-PTC based on PDB IDs 4LO4, 4LO7, 4LO8, 4LO0 (RCSB.org; accessed on 29 February 2024); Lee et al. [45] and PDB ID 3V0A (RCSB.org; accessed on 29 February 2024); Gu et al. [31]).