. 2024 Jun 18;16(6):975. doi: 10.3390/v16060975

Table 2.

Cell lines, viral integration sites, and disrupted host genes.

VIS	Cell Line
	Cervix				Oropharynx		Liver		T-Cell
	SiHa	HeLa	CaSki	DoTc2	2A3	SCC154	3B2	SNU-182	ACH-2
1	13q22.1 ^1,2,3 LINC00393 ⁴ KLF12 ⁵	8q24.21 ^2,3 PCAT1 ⁴ CASC19 ⁴ MYC ⁵	2p11.2 LINC01830 PRR30	2p22.3 LINC00486 ⁴	12q24.33 ¹ FBRSL1	6p12.2 7SK ⁴	4q13.3 ⁶	1q25.1 ¹ TNR	7p14.3 NT5C3A FKBP9 ⁵ RP9 ⁵
2	21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx	21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx	3q23 ⁶	3p25.1 ¹ ANKRD28 ⁴ RN7SL4P ⁴	16p13.3 METTL26	8q24.3 ^1,2 HGH1 ⁴	13q31.3 ⁵	2q34 UNC80 ⁴
3			6p21.1 ⁶	4p15.31 ¹ IGFBP7 ⁵	20q11.23 ¹ RPN2 ⁴	14q21.3 RN7SL2 ⁴	16q11.2 ⁶	4q31.3 ⁵
4			10p14 ⁶	6p21.32 ZBTB22	21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx	21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx	21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx	8q24.13 ^1,2 HAS2-AS1 ⁴
5			11p15.4 ⁶	7q21.3 GNGT1 ⁴	22q11.22 PPIL2 ⁴	21q21.1 ⁷	Yq12 ⁶	17p11.1 ⁶
6			14q21.3 MDGA2 ⁴	8p11.21 PLAT ⁴ HGH1 ⁴				21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx
7			19q13.42 ¹ BRSK1 ⁴	9p23 PTPRD ⁴ RN7SL5P RMRP ⁴
8			20p11.1 ⁶	10q26.11 ¹ TUBGCP2 ⁴ RGS10 ⁴
9			Xq27.3 ^1,6	14q21.3 RPPH1 ⁴ RN7SL2 ⁴ RPS29 ⁴ RN7SL1 ⁴
10				16p13.3 METTL26
11				21p11.2 ² MIR3648-1 ⁵ RNA5-8SNx
12				22q11.22 PPIL2 ⁴
13				Xq21.2 DACH2 ⁴

VIS, viral integration site numbered in sequence; x, 1 to 3. ¹ Chromosomal region and band recognized as a human common fragile site [41]. ² Chromosomal region and band associated with carcinogenesis [44,45,46,47,48,49]. ³ Chromosomal region and band recognized as an HPV integration hotspot (i.e., 2q22.3, 3p14.2, 3q28, 8q24.21, 8q24.22, 13q22.1, 14q24.1, 17p11.1, 17q23.1, and 17q23.2) [42]. ⁴ Disrupted oncogenic, tumor suppressor, or cancer-associated gene(s) [44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78]. ⁵ Nearby oncogenic, tumor suppressor, or cancer-associated gene(s) [44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78]. ⁶ Viral integration site without disrupted gene(s). Nearby genes listed in Supplementary Table S4. ⁷ Disrupted uncharacterized long non-coding RNA gene listed in Supplementary Table S4.