Figure 4.

(A) In vivo fluorescence imaging of tumor and muscle tissues before and after injected with FITC and HTP-BM/CFN respectively in mice and their fluorescent quantitative analysis (B). (C) In vivo fluorescence image along the time (0-6 h) after administrated with FITC and HTP-BM/CFN respectively, followed by light irradiation at 6h for fluorescence enhancement and their fluorescence quantification(D). (E) fluorescence quantification. (F) In vivo fluorescence image of light-modulated heterogeneous tumor imaging. (G) Real-time fluorescent imaging-guided tumor surgical resection based on the light-modulated fluorescence compensation of HTP-BM/CFN and fluorescent quantitative analysis of main organs and tumor. (*** p<0.001)