Table 4.

Risk factor analysis

A. Multinomial logistic regression for the prediction of drug resistance
Factors	Total	Odds Ratio	CI (95%)	p-Value
Multidrug resistance (MDR)a (n = 201)
History of surgery	48	2.73	(1.33–5.58)	0.006*
History of chemotherapy	71	4.95	(2.15–11.40)	0.000*
Recent antibiotic use	157	2.46	(1.74–6.48)	0.001*
Prior hospitalization	164	2.93	(1.08–7.92)	0.034*
Type of bacteria	50	23.44	(3.76-145.84)	0.001*
Neutropenia (ANC < 500)	08	1.24	(1.04–1.42)	0.009*
Extensively drug resistance (XDR)a (n = 124)
History of surgery	13	1.92	(1.56–4.53)	0.040*
History of chemotherapy	43	3.84	(1.48–9.96)	0.006*
Recent antibiotic use	106	3.43	(1.65–10.84)	0.021*
Prior hospitalization	103	3.87	(1.25-12.00)	0.019*
Neutropenia (ANC < 500)	05	1.34	(1.12–1.61)	0.001*
B. Binomial logistic regression for predictor analysis of 30-day mortality
Cancer recurrence	66	27.65	(2.00-38.75)	0.013*
Sepsis	36(1.33)	6.79	(1.23–37.68)	0.028*
Chemotherapy	148(32.7)	3.54	(1.06–11.80)	0.039*
Foley catheter Ryles tube Central venous catheter	274(36.81) 143(15.68) 33 (2.72)	4.13 2.74 12.51	(1.72–9.92) (1.18–6.33) (2.85–54.96)	0.002* 0.018* < 0.001*
NCI category-III NCI category-IV Neutrophilia	11(2.7) 41(7.0) 228(47.0)	1.09 1.39 1.26	(0.08–14.23) (0.08–1.89) (0.11–0.63)	0.045 0.002 0.003
MASCC score (< 21)	174(31.3)	2.49	(1.08–5.73)	0.032*
Klebsiella pneumoniae	94(17.3)	1.40	(0.46–2.20)	0.040
Pneumonia	55(0.3)	2.10	(1.20–4.10)	0.018*
VAP	11(9.7)	2.35	(0.75–3.25)	0.032
Polymicrobial	89(17.3)	1.58	(0.36–2.35)	0.027
Community acquired	113(21.3)	1.53	(0.49–4.70)	0.012
MDR isolates XDR isolates	201(35.11) 124(13.09)	3.40 8.12	(2.12–5.44) (4.11–16.06)	< 0.001* < 0.001*

* p value less than 0.05 indicates statistical significance. Abbreviations: NCI- National Cancer Institute, MASCC- Multinational Association for Supportive Care in Cancer, VAP- Ventilator-associated pneumonia, MDR- Multidrug resistant, XDR- Extensively drug resistant