Visibility of breast lesions in low-energy contrast-enhanced mammography (CEM) images, depending on the ACR category. White arrows mark suspicious lesions; all lesions had a histopathological diagnosis of invasive carcinoma NST. A) ACR A, clearly visible, small, irregular focal lesion, not obscured by fibro-glandular tissue. B) ACR B, an irregular lesion clearly visible against the background of fibro-glandular tissue. C) ACR C, a small, irregular focal lesion with a density similar to fibro-glandular tissue. D) ACR D, a lesion that is very poorly distinguished against the background of extremely dense fibro-glandular tissue, visible only as an area of architectural distortion