Different types of background parenchymal enhancement (BPE): (A) minimal, (B) mild, (C) moderate, and (D) marked. Visibility of breast lesions in recombined contrast-enhanced mammography (CEM) images, depending on the BPE type: (E) a low enhancing spicular lesion (white arrow) clearly visible on the background of minimal BPE (invasive carcinoma NST), (F) a moderate enhancing, irregular lesion (white arrow) on the background of mild BPE (invasive carcinoma NST), (G) a high enhancing, indistinct lesion (white arrow) on the background of moderate BPE (invasive lobular carcinoma), (H) a moderate enhancing, obscured lesion (white arrow) poorly distinguished on the background of marked BPE (ductal carcinoma in situ)