Figure 4.

A 50-year-old patient with a palpable tumour on the border of the upper quadrants. A) Low-energy contrast-enhanced mammography (CEM) image, the white arrow indicates an area of architectural distortion, poorly distinguishable against the fibro-glandular tissue. B) CEM recombined image, white arrow indicates a spicular, strongly enhancing tumour, much larger than in low-energy images. C) Lobules dilated by neoplastic cells (lobular carcinoma in situ) surrounded by diffuse, inconspicuous infiltration of invasive lobular carcinoma