Table 3.
Diagnostic performance of CEM in the assessment of patients with all breast density categories and with extremely dense breasts
| All densities | ACR D | |||
|---|---|---|---|---|
| Enhancement | + | – | + | – |
| n (%) | 562 (69.6) | 246 (30.4) | 56 (65.1) | 30 (34.9) |
| Malignant, n (%) | 409 (72.8) | 16 (6.5) | 36 (64.3) | 1 (3.35) |
| Benign, n (%) | 153 (27.2) | 230 (93.5) | 20 (35.7) | 29 (96.7) |
| ORmalignant+(e+ vs e-) (± 95% CI) | 38.5 (22.4-65.9) | 52.2 (6.6-412.4) | ||
| Sensitivity (± 95% CI) | 96.2% (93.8-97.7) | 97.3% (84.2-99.8) | ||
| Specificity (± 95% CI) | 60.0% (54.9-65.0) | 59.2% (44.2-72.7) | ||
| PPV (± 95% CI) | 72.8% (68.8-76.4) | 64.3% (50.3-76.3) | ||
| NPV (± 95% CI) | 93.5% (89.4-96.1) | 96.7% (80.9-99.8) | ||
| p | < 0.001 | < 0.001 | ||
PPV – positive predictive value, NPV – negative predictive value, CI – confidence interval, OR – odds ratio