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Anti-angiogenic activity of compounds 7, 8, and 21 in human endothelial progenitor cells.
| Compounds | IC50 (μM) a |
|---|---|
| 7 | 0.44 ± 0.01*** |
| 8 | 0.47 ± 0.03*** |
| 21 | 0.53 ± 0.01*** |
| Sorafenib | 5.50 ± 1.50 |
Human endothelial progenitor cells were treated with the indicated compounds for 48 h. Anti-angiogenic activity was evaluated in a cell growth assay. Data are displayed as the mean ± SEM. Sorafenib, a well-known anti-angiogenic agent, was used as a positive control.
