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. 2023 Dec 22;46(2):e20230104. doi: 10.1590/2175-8239-JBN-2023-0104en

Table 2. Mean serum levels (before dialysis sessions) of uremic solutes in patients enrolled in the HDFit trial: HDF vs. HD.

Biomarker Impact of HDF compared to high-flow HD
Kt/V Increase of 0.1 unit in 6 months
URR (%) 2.5% reduction in 6 months
Phosphorus (mg/dL) Reduction of 0.4 mg/dL in 3 months
P-cresyl sulfate (umol/L) Reduction of 2.4 umol/L per month
Indoxyl sulfate (umol/L) Reduction of 2.9 umol/L per month
Beta-2 microglobulin (mg/L) Reduction of 1.6 mg/L per month

Monthly averages describe the mean differences during six months of follow-up. URR: urea removal rate. *Subgroup of patients with median convection volume > 27.5 L/session.