Table 1.
On bead flow cytometry data for cytokines in plasma-derived sEV from HNSCC patientsa.
| Mean (± sd) RFV (N = 6 HNSCC patients) | ||
|---|---|---|
| Surface | Total | |
| IL1β | 1.0 ( ± 0.1) | 1.3 ( ± 0.6) |
| IL6 | 2.7 ( ± 1.4) | 6.0 ( ± 1.9) |
| IL8 | 1.6 ( ± 0.5) | 7.1 ( ± 3.5) |
| IL10 | 3.0 ( ± 0.5) | 8.8 ( ± 3.8) |
| IL17 | 2.2 ( ± 1.0) | 8.7 ( ± 1.6) |
| IFNγ | 1.4 ( ± 0.3) | 1.7 ( ± 0.3) |
| MCP-1 | 3.2 ( ± 0.9) | 0.8 ( ± 0.1) |
| TNFα | 1.2 ( ± 0.1) | 0.9 ( ± 0.1) |
| TGFβ | 2.4 ( ± 0.9) | 1.4 ( ± 0.6) |
asEV were isolated from plasma of six HNSCC patients, and the MFI of each cytokine was determined by on-bead flow cytometry. Relative fluorescence intensity values (RFVs) were calculated as MFI of stained sample/MFI of isotype control.