Table 3.

Correlation between cytokine levels in sEV and the difference in level between detergent-treated and untreated plasma.

Protein	Target group	rho	P value^a
G-CSF	Cytokines	0.36	0.06
GM-CSF	Cytokines	−0.03	0.87
IFNa	Cytokines	0.44	0.02
IFNg	Cytokines	0.44	0.02
IL-12p70	Cytokines	0.43	0.02
IL-13	Cytokines	0.16	0.40
IL-15	Cytokines	0.94	<.0001
IL-16	Cytokines	0.34	0.07
IL-17a	Cytokines	0.82	<.0001
IL-18	Cytokines	0.15	0.44
IL-2	Cytokines	0.19	0.33
IL-20	Cytokines	0.32	0.09
IL-21	Cytokines	0.79	<.0001
IL-22	Cytokines	0.43	0.02
IL-27	Cytokines	0.03	0.89
IL-3	Cytokines	0.42	0.02
IL-6	Cytokines	0.93	<.0001
IL-7	Cytokines	0.53	0.003
IL-9	Cytokines	0.82	<.0001
IP-10	Cytokines	0.15	0.44
LIF	Cytokines	0.26	0.18
MIF	Cytokines	0.15	0.45
TNFa	Cytokines	0.15	0.45
TSLP	Cytokines	0.05	0.78
BCL	Chemokines	0.20	0.30
ENA-78	Chemokines	0.03	0.89
Eotaxin	Chemokines	0.75	<.0001
Eotaxin-2	Chemokines	0.21	0.27
Eotaxin-3	Chemokines	0.50	0.01
Fractalkine	Chemokines	0.43	0.02
I-TAC	Chemokines	0.60	0.001
MCP-1	Chemokines	0.32	0.09
MCP-2	Chemokines	0.26	0.17
MCP-3	Chemokines	1.00	<.0001
MDC	Chemokines	0.01	0.95
MIP-1a	Chemokines	0.29	0.13
MIP-1b	Chemokines	0.84	<.0001
MIP-3a	Chemokines	0.05	0.81
SDF-1a	Chemokines	0.90	<.0001
FGF-2	Growth factors/regulators	−0.02	0.93
HGF	Growth factors/regulators	0.54	0.003
NGFb	Growth factors/regulators	0.15	0.45
SCF	Growth factors/regulators	0.33	0.08
VEGF-A	Growth factors/regulators	0.82	<.0001
APRIL	Soluble receptors	0.74	<.0001
CD30	Soluble receptors	0.44	0.02
CD40L	Soluble receptors	0.07	0.72
IL-2R	Soluble receptors	0.34	0.08
TNFRII	Soluble receptors	0.72	<.0001
TRAIL	Soluble receptors	0.34	0.07
TWEAK	Soluble receptors	0.40	0.03

^aPearson correlation.