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. 2024 Jun 27;19(6):e0305898. doi: 10.1371/journal.pone.0305898

Table 1. Characteristics of NL cohort in 2016 and 2019 and comparison with CANOC.

Characteristic Category Descriptive Statistics
NL 2016 NL 2019 CANOC 2016
n = 177 n = 188 n = 11768
n (%) n (%) n (%)
Age (years) Median (IQR) 50 (44–55) 53 (46–57) 47 (38–54)b
Gender Male 137 (77) 143 (76) 9744 (83)
  Female 40 (23) 44 (23) 1963 (17)
  Transgender 0 (0) 1 (1) 55 (0)
  Unknown 0 (0) 0 (0) 6 (0)
Born In Canada No 12 (7) 17 (9) 1512 (13)
  Yes 163 (92) 165 (88) 2513 (21)
  Unknown 2 (1) 6 (3) 7743 (66)
HIV Risk MSM   91 (51) 100 (53) 5669 (48)
HIV Risk Heterosexual   78 (44) 71 (38) 2538 (22)
HIV Risk IDU   19 (11) 14 (7) 2478 (21)
HIV Risk Blood products   4 (2) 5 (3) 177 (2)
HIV Risk Endemic country   11 (6) 16 (9) 726 (6)
HIV Risk Perinatal transmission   1 (1) 2 (1) 8 (0)
Age of Starting cART (years) Median (IQR) 37 (31–45) 37 (31–46) 39 (32–47)b
Baseline CD4+ T cell (cells/μL) Median (IQR) 384 (160–529) 364 (164–558) N/A
HIV Duration (years) Median (IQR) 13 (4–22) 15 (6–25) 8 (4–13)b
CD4+ T cell (cells/mL) Median (IQR) 621 (396–820) 672 (422–920) N/A
Time to cART Initiation 0–12 months 121 (68) 124 (66) 2682 (23)
> 12 months 48 (27) 48 (26) 4122 (35)b
Unknown 8 (5) 16 (9) 4964 (42)
Duration on cART (years) Median (IQR) 11 (3–18)a 11 (5–21) 6 (3–10)b
Ever Diagnosed with AIDS-defining Illness 41 (23) 46 (24) 2208 (19)
On cART  175 (99) 184 (98) 10190 (99)
On cART and undetectable viremia 162 (93) 176 (96) 8889 (87)
Hepatitis B (ever co-infected) 17 (10) 18 (10) 1314 (11)
Hepatitis C (ever co-infected) 20 (11) 19 (10) 2644 (22)b
Cytomegalovirus IgG Never co-infected 29 (16) 28 (15) N/A N/A
  Coinfected 144 (81) 155 (82) N/A N/A
  Unknown 4 (2) 5 (3) N/A N/A
Ever Diagnosed with Cancer 15 (8) 17 (9) 380 (3)b

aDenotes p < 0.05 for significant difference in comparing NL (2016) vs NL (2019).

bDenotes p < 0.05 for significant difference in comparing NL (2016) vs. CANOC (2016) and associated with probability of indicated cohort more likely to have the higher value.