Skip to main content
. 2024 Jun 27;19(6):e0296196. doi: 10.1371/journal.pone.0296196

Fig 7. Increased BOLD signals during working memory processing as a function of time points and task difficulty.

Fig 7

Nine clusters were selected from all the clusters identified via searchlight analyses. (A) Six selected clusters in the non-HU control group had higher brain activation during working memory processing at 1-year follow-up than at pre-treatment. However, only 1 cluster had higher brain activation in the HU group at 1-year follow-up compared to pre-treatment. * p < .05 [Wilcoxon signed-rank test within the HU group (red) or the non-HU control group (gray)]. (B) Increased BOLD signals were observed in most selected clusters in both groups, as the working memory load increased from 0- to 1-back. In the non-HU control group, BOLD signals did not increase further when the working memory load increased from 1- to 2-back. In the HU group, however, BOLD signals increased continuously as the working memory load increased from 0- to 2-back. # p < .05 (Wilcoxon signed-rank test).