Table 1.
Summary of studies comparing conduction system pacing and RVP with echocardiographic findings
| Authors | Study type | No. of patients | Compared types | Pacing indication | Follow-up | Outcomes | ΔLVEF | LVEF |
|---|---|---|---|---|---|---|---|---|
| Catanzariti et al.8 | Prospective, intrapatient acute comparison | 23 | RVP, HBP and mHBP | SND, AVB, or AF with slow rate | IVD, SPD, and TDId | |||
| Occhetta et al.44 | Crossover, patient blind, randomized | 18 | RVP and HBP | AVN ablation for AF | 6 months | EF, IVD, MR, and TR | 52% baseline to 50% RVP and 53.4% HBP (P = ns) | |
| Zanon et al.45 | Prospective, crossover mid-term | 12 | RVP and HBP | AVB or AF with slow rate | 3 months | LVEF, myocardial dyssynchrony | 59.8% baseline to 61% RVP and 63% HBP (P > 0.05) | |
| Kronborg et al.24 | Prospective, randomized, single-centre crossover | 34 | RVP and HBP | AVB | 12 months | LVEF, time-to-peak systolic velocity | 50% RVP and 55% HBP (P = 0.005) | |
| Vijayaraman et al.26 | Observational, retrospective, case–control | 173 | RVP and HBP | Bradycardia | 5 years | LVEF | 57% baseline to 52% (RVP; P = 0.002) and 55% (HBP; P = 0.13) | |
| Das et al.48 | Prospective, single centre | 50 | RVP and LBBAP | Bradycardia | 6 months | LVEF, LVEDd, IVD | 60% RVP and 64% LBBAP (P = 0.013) | |
| Mao et al.49 | Observational, two-centre | 82 | RVP and LBBAP | Bradycardia | 1 year | ΔLVEF, LVGLS | −7.4 and 0.3% (P < 0.01) | 58% RVP and 65% LBBAP (P < 0.01) |
| Ponnusamy et al.50 | Retrospective, two-centre | 121 | RVP, HBP, and LBBAP | Bradycardia | 4 weeks | ΔLVEF | −4%, + 5%, + 4 (RVP, HBP, LBBAP, P = 0.001) |
AF, atrial fibrillation; AVB, atrioventricular blockage; AVN, atrioventricular node; CSP, conduction system pacing; EF, ejection fraction; HBP, His bundle pacing; IVD, interventricular dimension; LBBAP, left bundle branch area pacing; LVEDd, left ventricular end-diastolic dimension; LVEF, left ventricular ejection fraction; LVGLS, left ventricular global longitudinal strain; mHBP, modified His bundle pacing (His bundle pacing + right ventricular pacing); MR, mitral regurgitation; RVP, right ventricular pacing; SND, sinus node dysfunction; SPD, septal to left posterior wall motion delay; TDId, maximal difference between tissue Doppler imaging systolic velocities of basal left ventricular segment; TR, tricudpid regurgitation.