FIG. 3.

KD1 and KD3 do not replicate well in nongrowing cells and primary human cells. (a to d) HEL-299 cells growing in 10% FBS or growth arrested in 0.2% FBS were infected with 100 PFU/cell of the indicated viruses. At the indicated days p.i., virus was extracted from cells, and titers were determined on A549 cells. (e) Human primary bronchial epithelial cells, infected at 30% confluency with 10 PFU of the viruses indicated at left per cell and photographed at 5 days p.i. (f) Human primary small airway epithelial cells infected at 50% confluency with the indicated virus (10 PFU/cell), 5 days p.i. (g) Human primary endothelial cells infected at confluency with the indicated virus (10 PFU/cell), 8 days p.i.