Table 1.
Demographic and clinical baseline characteristics.
| Healthy group n = 32 | HDO group n = 27 | p value | |
|---|---|---|---|
| Age, years | 34 [30;36] | 36 [33;39] | 0.049 |
| Height, meters | 1.64 [1.60;1.69] | 1.66 [1.60;1.70] | 0.492 |
| Pre-pregnancy body mass index, kg/m2 | 22.3 [20.8;24.3] | 27.2 [22.2;31.7] | 0.001 |
| Cardiovascular risk factors | |||
| Arterial hypertension n (%) | n/a | 16 (59.3) | n/a |
| Obesity n (%) | n/a | 11 (40.7) | n/a |
| Gestational diabetes n (%) | n/a | 12 (44.4) | n/a |
| Type 2 Diabetes n (%) | n/a | 1 (3.7) | n/a |
| Pharmacological therapy during pregnancy | |||
| Aspirin | 4 (12.5) | 14 (51.9) | 0.002 |
| Metformin | 0 (0.0) | 11 (20.0) | < 0.001 |
| Insulin | 0 (0.0) | 10 (18.2) | < 0.001 |
| Beta-blockers | 0 (0.0) | 2 (7.4) | 0.205 |
| Nifedipine | 0 (0.0) | 1 (3.7) | 0.458 |
| Smoking habits | |||
| Non-smoker n (%) | 18 (56.3) | 20 (74.1) | 0.477 |
| Smoker n (%) | 3 (9.4) | 2 (7.4) | |
| Stopped only during pregnancy n (%) | 1 (3.1) | 1 (3.7) | |
| Stopped at pregnancy beginning n (%) | 2 (6.3) | 2 (7.4) | |
| Ex-smoker n (%) | 8 (25.0) | 2 (7.4) | |
| Primiparous women n (%) | 15 (46.9) | 15 (55.6) | 0.604 |
| Pregnancy weeks at delivery | 39 [31;33] | 39 [38;40] | 0.291 |
| Type of delivery | |||
| Vaginal delivery n (%) | 19 (59.4) | 20 (74.1) | 0.279 |
| Caesarean delivery n (%) | 13 (40.6) | 7 (25.9) | |
| Evaluation moment | |||
| Pregnancy, weeks | 31 [32;39] | 32 [32;34] | 0.146 |
| Postpartum, months | 7 [6;8] | 6 [6;7] | 0.033 |
Values expressed by median [interquartile range].
Significant values are in bold.