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. 2024 Jun 14;15:1358278. doi: 10.3389/fendo.2024.1358278

Table 6.

Multivariate regression analysis of fixed and flexible protocol of GnRH antagonist.

Before PSM After PSM
Fixed protocol Coefficient t P Coefficient t P
OPU number 0.003 0.126 0.900 -0.002 -0.061 0.951
Number of usable embryos -0.020 -0.780 0.436 0.008 0.237 0.813
Number of good quality embryos 0.029 0.968 0.333 0.039 1.037 0.300
Wald value 95% CI P Wald value 95% CI P
OHSS 0.759 0.097, 2.451 0.384 2.633 0.837, 6.637 0.105
Clinical pregnancy 0.486 0.626, 1.250 0.486 0.388 0.581, 1.325 0.877
Live birth 0.001 0.700, 1.417 0.982 3.531 0.958, 7.604 0.060
Multiple pregnancy 0.189 0.560, 2.485 0.664 2.402 0.798, 6.881 0.121
Miscarriage 2.006 0.266, 1.238 0.157 3.757 0.128, 1.012 0.053
Flexible protocol Coefficient t P Coefficient t P
OPU number 0.000 -0.023 0.982 -0.034 -1.444 0.149
Number of usable embryos 0.031 1.576 0.115 0.041 1.826 0.068
Number of good quality embryos 0.023 0.979 0.328 0.044 1.538 0.124
Wald value 95% CI P Wald value 95% CI P
OHSS 0.076 0.516, 1.648 0.783 0.163 0.555, 2.444 0.686
Clinical pregnancy 0.521 0.679, 1.196 0.470 0.820 0.610, 1.199 0.365
Live birth 0.296 0.695, 1.228 0.587 0.247 0.420, 1.677 0.619
Multiple pregnancy 1.273 0.783, 2.485 0.259 0.027 0.457, 1.940 0.942
Miscarriage 0.260 0.656, 2.048 0.610 0.307 0.630, 2.286 0.580

PSM, propensity score matching; OPU, oocytes pick up; OHSS, ovarian hyper-stimulation syndrome; 95% CI, 95% confidential interval.