Example of a 47-year-old man who presented with atypical chest pain, hypertension and dyslipidemia.
(A): CCTA shows stenosis (arrow) is caused by a mixed plaque of the proximal LAD; (B): invasive coronary angiography shows severe stenosis (arrow) with ischemia in LAD (FFR = 0.74); (C): stress-CTP shows myocardial blood flow; (D): CTP-FFR demonstrates value of 0.76 in the LAD. CCTA: coronary computed tomography angiography, CTP: CT perfusion, FFR: fractional flow reserve; LAD: left anterior descending. Reprinted with permission under open access from Go et al.[219]