Table 3. Association of Each Additional Day of Early Antibiotic Exposure With Neonatal Outcomes Among Infants With Low Risk of Early-Onset Sepsis.

Outcomesa	Unadjusted OR (95% CI)	aOR (95% CI)
		Model 1b	Model 2c
Moderate to severe BPD or death	1.17 (1.12-1.22)	1.16 (1.10-1.21)	1.10 (1.04-1.16)
Moderate to severe BPD in survivors at 36 wk PMA	1.17 (1.12-1.23)	1.16 (1.10-1.22)	1.10 (1.04-1.16)
Death prior to 36 wk PMA	1.11 (0.99-1.24)	1.04 (0.92-1.18)	1.00 (0.87-1.14)
Death before hospital discharge	1.12 (1.01-1.25)	1.08 (0.96-1.21)	1.04 (0.91-1.18)

Abbreviations: aOR, adjusted odds ratio; BPD, bronchopulmonary dysplasia; OR, odds ratio; PMA, postmenstrual age.

^a Logistic regression models were used to analyze the categorical variables.

^b Adjusted for gestational age, birthweight, small for gestational age, sex, multiple pregnancy, maternal age, gestational diabetes, gestational hypertension, preeclampsia or eclampsia, antenatal corticosteroids use, and magnesium sulfate use.

^c Adjusted for same variables as model 1 plus Apgar score, intubation in delivery room, treatment with surfactant, nitric oxide, patent ductus arteriosus requiring pharmacological treatment, and mechanical ventilation treatment in 7 days after birth.