Table 3.

Effects of age and depressive symptoms on functional connectivity.

	Model 1			Model 2
	B	SE B	β	B	SE B	β
vmPFC
Left Amygdala
Positive
Age	0.015	0.006	0.343a	0.014	0.006	0.330
CESD-R	0.014	0.007	0.275	0.014	0.007	0.278
Age x CESD-R	–	–	–	0	0	−0.057
R 2		0.139			.142
F for ΔR2		4.04a			0.176
Negative
Age	0.002	0.006	0.055	0.001	0.006	0.017
CESD-R	0.004	0.007	0.076	0.004	0.007	0.089
Age x CESD-R	–	–	–	0	0	−0.151
R 2		0.006			0.027
F for ΔR2		0.160			1.047
Right Amygdala
Positive
Age	0.006	0.005	0.168	0.006	0.006	0.166
CESD-R	0.010	0.006	0.222	0.010	0.006	0.222
Age x CESD-R	–	–	–	−0.00002	0	−0.008
R 2		0.056			0.056
F for ΔR2		1.480			0.003
Negative
Age	0.001	0.004	0.020	0	0.005	−0.004
CESD-R	0.0001	0.005	0.001	0	0.005	0.010
Age x CESD-R	–	–	–	0	0	−0.096
R 2		0			0.009
F for ΔR2		0.010			0.422
VOTC
Positive
Age	0.002	0.008	0.036	0.002	0.008	0.040
CESD-R	0.00002	0.009	0	−0.00005	0.009	−0.001
Age x CESD-R	–	–	–	0.00005	0	0.014
R 2		.001			0.001
F for ΔR2		0.033			0.008
Negative
Age	−0.003	0.008	−0.060	−0.002	0.008	−0.036
CESD-R	−0.001	0.009	−0.018	−0.002	0.009	−0.027
Age x CESD-R	–	–	–	0	0.001	0.098
R 2		0.003			0.012
F for ΔR2		0.084			0.437
Hippocampus
Positive
Age	0.002	0.004	0.085	0.001	0.004	0.059
CESD-R	0	0.004	0.014	0.001	0.004	0.023
Age x CESD-R	–	–	–	0	0	−0.105
R 2		.007			0.017
F for ΔR2		0.171			0.503
Negative
Age	−0.004	0.003	−0.163	−0.004	0.003	−0.194
CESD-R	−0.001	0.004	−0.033	−0.001	0.004	−0.022
Age x CESD-R	–	–	–
R 2		0.025			0.039
F for ΔR2		0.631			0.712
dmPFC
Left Amygdala
Positive
Age	−0.003	0.006	−0.066	−0.003	0.006	−0.079
CESD-R	0.005	0.007	0.094	0.005	0.007	0.095
Age x CESD-R	–	–	–	0	0	−0.063
R 2		0.017			0.021
F for ΔR2		0.463			0.199
Negative
Age	−0.006	0.006	−0.141	−0.007	0.006	−0.157
CESD-R	0.010	0.007	0.201	0.010	0.007	0.202
Age x CESD-R	–	–	–	0	0	−0.078
R 2		0.078			0.084
F for ΔR2		2.250			0.328
Right Amygdala
Positive
Age	0.006	0.005	0.159	0.006	0.006	0.162
CESD-R	0.016	0.006	0.345a	0.016	0.006	0.345a
Age x CESD-R	–	–	–	0.00004	0	0.015
R 2		0.109			0.109
F for ΔR2		3.25a			0.012
Negative
Age	0.001	0.006	0.028	0.001	0.007	0.034
CESD-R	0.009	0.007	0.178	0.009	0.007	0.177
Age x CESD-R	–	–	–	0.0001	0	0.026
R 2		0.029			0.030
F for ΔR2		0.796			0.034
VOTC
Positive
Age	−0.004	0.008	−0.078	−0.003	0.008	−0.065
CESD-R	0.006	0.009	0.093	0.006	0.009	0.092
Age x CESD-R	–	–	–	0	0	0.058
R 2		0.019			0.023
F for ΔR2		0.522			0.173
Negative
Age	−0.024	0.009	−0.358a	−0.020	0.009	−0.301a
CESD-R	−0.008	0.010	−0.100	−0.008	0.010	−0.105
Age x CESD-R	–	–	–	0.001	0.001	0.266a
R 2		0.115			0.182
F for ΔR2		3.444a			4.273a
Hippocampus
Positive
Age	−0.002	0.004	−0.061	−0.003	0.004	−0.099
CESD-R	0.005	0.005	0.137	0.005	0.005	0.141
Age x CESD-R	–	–	–	0	0	−0.179
R 2		0.028			0.058
F for ΔR2		0.760			1.677
Negative
Age	−0.011	0.004	−0.350a	−0.011	0.004	−0.358a
CESD-R	−0.002	0.005	−0.069	−0.002	0.005	−0.068
Age x CESD-R	–	–	–	−0.0001	0	−0.033
R 2		0.112			0.113
F for ΔR2		3.346a			0.063

Note. All conditions presented in the table are relative to the neutral valence condition. Seed regions appear in bold text.

Key: dmPFC, dorsomedial prefrontal cortex; vmPFC, ventromedial prefrontal cortex, VOTC, ventral occipitotemporal cortex.

^ap < 0.05