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. 2024 May 30;15(13):4072–4080. doi: 10.7150/jca.95339

Figure 1.

Figure 1

GNL3L is highly expressed in AML as a poor prognostic factor and associated with active NF-κB pathway. (A) The mRNA expression of GNL3L is up-regulated in AML in TCGA database. High expression of GNL3L predicts poor prognosis both in AML-TCGA database (B) and GSE71014 (C). (D) Venn chart of shared differentially expressed genes (DEGs) in AML-TCGA and GSE71014 dataset, including RELA. (E) GSEA shows NF-κB pathway is enriched in GNL3L high expression AML group. (F) The expression of GNL3L and RELA is significantly correlated in AML-TCGA.