Table 5.
Comparison of baseline characteristics between death and survival groups*
| Characteristics | BCOS (n = 171) | Death group (n = 32) | Survival group (n = 139) | P-value |
|---|---|---|---|---|
| Age in years |
67 (61–72) |
70 (65–75) |
66 (60–71) |
0.010 |
| Male, n (%) |
133 (77.8) |
27 (84.4) |
106 (76.3) |
0.319 |
| BMI (kg/m2) |
20.90 (18.60–23.50) |
18.70 (16.80–22.30) |
21.20 (19.30–23.60) |
0.022 |
| Previous/current smokers, n (%) |
110 (64.3) |
21 (65.6) |
89 (64) |
0.865 |
| Smocking pack-years |
20 (0–40) |
30 (0–40) |
20 (0–40) |
0.892 |
| First diagnosis before 50 y old, n (%) |
11 (6.4) |
3 (9.4) |
8 (5.8) |
0.452 |
| Hospitalisation days |
10 (8–12) |
12 (9–15) |
10 (8–11) |
0.003 |
| Times of exacerbations in the past 12 mo |
1 (1–3) |
2 (1–3) |
1 (1–2) |
0.192 |
| CAT score for admission |
22 (17–27) |
26 (18–31) |
21 (17–26) |
0.038 |
| mMRC dyspnoea grade for admission |
3 (2–4) |
3 (3–4) |
3 (2–3) |
0.013 |
| Improvements in CAT score |
7 (3–12) |
7 (6–8) |
7 (3–12) |
0.464 |
| Improvements in mMRC dyspnoea grade |
1 (0–1) |
0 (0–1) |
1 (0–1) |
0.260 |
| CAT score for discharge |
14 (10–20) |
22 (14–25) |
14 (9–18) |
0.006 |
| mMRC dyspnoea grade for discharge |
2 (1–3) |
3 (3–4) |
2 (1–2) |
<0.001 |
| FEV1% predicted |
33.40 (26.40–44.70) |
31.70 (25.50–41.70) |
33.90 (26.80–45.00) |
0.471 |
| FVC (L) |
1.94 (1.43–2.38) |
1.64 (1.34–2.16) |
1.96 (1.45–2.39) |
0.152 |
| FEV1/FVC |
43.40 (34.20–60.00) |
43.30 (37.50–53.00) |
43.50 (33.90–60.20) |
0.898 |
| Comorbidities, n (%) |
|
|
|
|
|
Hypertension
|
49 (28.7) |
10 (31.3) |
39 (28.1) |
0.719 |
|
Diabetes mellitus
|
20 (11.7) |
4 (12.5) |
16 (11.5) |
0.875 |
|
Obsolete pulmonary tuberculosis
|
52 (30.4) |
17 (53.1) |
35 (25.2) |
0.002 |
|
Active pulmonary tuberculosis
|
6 (3.5) |
1 (3.1) |
5 (3.6) |
0.896 |
|
Coronary artery disease
|
23 (13.5) |
3 (9.4) |
20 (14.4) |
0.454 |
|
Arrhythmia
|
11 (6.4) |
3 (9.4) |
8 (5.8) |
0.452 |
|
Pulmonary heart disease
|
32 (18.7) |
13 (40.6) |
19 (13.7) |
<0.001 |
| Medication |
|
|
|
|
|
Inhalation of bronchodilators
|
119 (69.6) |
17 (53.1) |
102 (73.4) |
0.025 |
|
ICS
|
83 (48.5) |
14 (43.8) |
69 (49.6) |
0.548 |
| Systemic hormone | 150 (87.7) | 26 (81.3) | 124 (89.2) | 1.529 |
BCOS – bronchiectasis-chronic obstructive pulmonary disease overlap syndrome, BMI – body mass index, CAT – chronic obstructive pulmonary disease assessment test, FEV1 – forced expiratory volume in one second, FVC – forced vital capacity, ICS – inhaled corticosteroids, IQR – interquartile range, MD – median, mMRC – modified Medical Research Council
*Presented as MD (IQR) unless specified otherwise.