Fig. 1.

Flowchart detailing selection of SCD_Winblad and SCD_Jak/Bondi samples. Abbreviations: SCD = Subjective cognitive decline; SCI = Subjective cognitive impairment; RAID = Rating Anxiety in Dementia scale; CSDD = Cornell Scale for Depression in Dementia; HADS-A = Hospital Anxiety and Depression Scale-Anxiety subscale; HADS-D = Hospital Anxiety and Depression Scale-Depression subscale. ^aMissing date of birth, visit date and/or diagnosis data. ^bOn the database, the term SCI, rather than SCD, is used (see Methods). ^cPatients with missing data for measures of affective symptomatology (i.e., RAID/CSDD or HADS-A/HADS-D) or case notes were excluded, as it was not possible to determine their fulfilment of the SCD research criteria