Table 1.
Winblad [13] MCI criteria used in the Essex Memory Clinic | Jak/Bondi [14] MCI criteria used for this study |
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1) Not normal, not demented (Does not meet criteria (DSM-IV, ICD-10) for a dementia syndrome) 2) Cognitive decline a. Self and/or informant report and impairment on objective cognitive tasks* and/or b. Evidence of decline over time on objective cognitive tasks 3) Preserved basic activities of daily living/minimal impairment in complex instrumental functions |
1) General cognitive and functional performance sufficiently preserved such that a diagnosis of dementia cannot be made 2) Cognitive decline a. Both scores fall more than 1 SD below the age-specific normative mean within a cognitive domain; or b. One score falls more than 1 SD below the age-specific normative mean in all of the cognitive domains sampled |
The Winblad criteria [13] are reproduced with permission from John Wiley and Sons. The Jak/Bondi criteria [14] are reproduced with permission from IOS Press. Abbreviations: MCI = mild cognitive impairment; DSM-IV = Diagnostic and Statistical Manual of Mental Disorders (4th edition); ICD-10 = International Statistical Classification of Diseases and Related Health Problems (10th Revision). *Whilst, for Winblad criteria, the clinic does not apply a rigid cut-off to classify MCI, cognitive scores falling below the 10th percentile (according to demographically-adjusted norms) are typically interpreted as impaired.