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. 2024 Apr 16;3(3):e117. doi: 10.1002/cai2.117

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© 2024 The Authors. Cancer Innovation published by John Wiley & Sons Ltd on behalf of Tsinghua University Press.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The expression of mitogen‐activated protein kinase 4 (MAPK4) in the tumor tissue of patients with clinical non‐small cell lung cancer (NSCLC). (a) The microarray of NSCLC tissues obtained from relevant patients was analyzed by multiplex immunofluorescence staining of CD34 and MAPK4. MAPK4 staining is shown in red, CD34 staining is shown in green, and 4′,6‐diamidino‐2‐phenylindole (DAPI) staining is shown in blue. Carcinoma tissues (1, 3, 5…17): 92 samples; paracarcinoma tissues (2, 4, 6…18): 88 samples. (b) The expression of MAPK4 in carcinoma and paracarcinoma clinical samples from patients with NSCLC were analyzed, and the H‐scores were calculated. (c) Comparison of MAPK4 expression in CD34‐positive cells between cancer and adjacent tissues. (d) The 5‐year overall survival rate in the four groups was determined through Kaplan–Meier analysis.