Table 2.

The results of linear regression for the lowest cell count

	ALC			WBC			NEU
	F	Adjusted R2 (SD)	P value	F	Adjusted R2 (SD)	P value	F	Adjusted R2 (SD)	P value
EDIC	28.710	0.209 (0.193)	< 0.001	8.587	0.067 (0.967)	0.004	5.441	0.041 (0.805)	0.022
V10	24.570	0.183 (0.196)	< 0.001	7.411	0.058 (0.972)	0.008	2.538	0.014 (0.836)	0.114
V20	22.471	0.170 (0.197)	< 0.001	6.114	0.046 (0.978)	0.015	2.094	0.010 (0.837)	0.151
V30	14.414	0.113 (0.204)	< 0.001	2.457	0.014 (0.994)	0.120	0.820	−0.002 (0.843)	0.367
V40	6.682	0.051 (0.211)	0.011	0.001	−0.010 (1.006)	0.977	0.194	−0.008 (0.845)	0.660
Sex (male vs. female)	3.877	0.027 (0.214)	0.052	1.761	0.007 (0.998)	0.187	3.147	0.020 (0.833)	0.079
Age (≤ 60 years vs. > 60 years)	0.171	−0.008 (0.218)	0.681	4.267	0.030 (0.986)	0.041	0.683	−0.003 (0.843)	0.410
Smoking history	3.588	0.024 (0.214)	0.061	0.788	−0.002 (1.003)	0.377	0.333	−0.006 (0.845)	0.565
Alcohol history	2.614	0.015 (0.215)	0.109	1.197	0.002 (1.000)	0.276	1.823	0.008 (0.839)	0.180
Tumor location (upper vs. others)	4.475	0.032 (0.213)	0.037	2.060	0.010 (0.996)	0.154	0.354	−0.006 (0.844)	0.553
GTV (≤ 48.4 cm3 vs. > 48.4 cm3)	1.522	0.005 (0.216)	0.220	1.525	0.005 (0.999)	0.220	0.408	−0.006 (0.844)	0.525
Clinical stage	1.842	0.008 (0.216)	0.178	1.502	0.005 (0.999)	0.223	0.003	−0.010 (0.846)	0.954
Chemotherapy regimen	0.195	−0.008 (0.218)	0.660	1.366	0.003 (1.000)	0.245	4.313	0.031 (0.829)	0.040

EDIC effective dose to immune cells; GTV, gross tumor volume